We're going to come straight out of the gate here and say that we do not recommend Liver Renew. It's an unfortunate example of why a lot of people simply don't trust natural supplements, being comprised of a proprietary blend that, despite housing some quality ingredients, ultimately fails to land.
It may be on the cheaper end of the spectrum, but we simply can't recommend an ineffective product. There are plenty of supplements on the market that contain the same effective ingredients as Liver Renew without tarnishing that with 15+ other ingredients battling for just 1,300mg of space.
With 22 ingredients, an even split would leave everything with less than 60mg each, though with our experience we believe it's more likely the first few ingredients are dosed somewhat reasonably (they have to be listed largest first legally), with the rest being placed with 1mg or so simply for marketing purposes. It's an unfortunate trend for proprietary blends, as if your customers can't see the doses, why bother dosing correctly?
Well luckily not all liver health supplements are like this, and typically we prefer Leber Cure. It's got a no nonsense approach to it's formula, including all of the A-list natural supplements that have been clinically proven to work. There's some shared ingredients between the two, such as artichoke leaf and milk thistle extract, with the difference being that with Leber Cure you can actually see how much of it you'll be getting per serving, meaning there's no fluff and you're actually getting a functional dose of the most well backed ingredients. This commitment to transparency in the formula shows that they trust in their product and more importantly, respect their customers properly. It's simply a better product, and although it's more expensive overall, you're getting a product that works and doesn't lie to you.
Proprietary Herbal Blend 1.3g
With propriatary blends there's often some confusion about dosing which can make them a little less trust worthy. That said, you can infer dosage as by law companies need to list the ingredients in volumetric order, meaning those at the top take up the most space, and those at the bottom take up the least. With 1.3g, there's seemingly a lot of space, but once you start to see recommended doses, you'll see how things fall off fast.
There are some good ingredients here that we'll be taking a close look at, but with 22 ingredients it's clear to see 1,300mg just isn't enough space to fit them all in at all in.
Though there is a lot evidence that burdock root has protective effects for the liver, it's difficult to really confirm whether these effects will be seen in anything but rats, as every study we found was animal studies. One such study treats the rats at 100 or 200mg/kg body weight, so without further human trials this is the best information we have for dosage .
By being the first ingredient in the proprietary blend, this means that it's the most abundant ingredient in said blend. Using this we can assume it's been dosed correctly, but we do need more evidence overall to confirm it's efficacy, and it's not a certainty that it is dosed correctly. There's 22 unique ingredients taking up just 1,300mg, so it's going to be a tight squeeze.
Artichoke Leaf Extract
One of the better researched therapeutic supplements for liver health, and is considered one of the better options for helping with chronic liver disease. It is capable or directly suppressing inflammation and Apoptosis during the development of fatty liver disease , has a positive effect of liver enzymes , and has been found to show antioxidant and protective effects on the liver as a whole .
The only worry here is dosage, and it's still pretty high up on the list so 300mg isn't unattainable, just unlikely. This would mean there would be 300mg or more burdock root, which would mean about 45% of this entire formula is made up of these two ingredients. It's either that, or they're ineffectively dosed.
Milk Thistle Extract
Similar to artichoke leaf, milk thistle extract is a well researched and as such, a well understood therapeutic treatment for liver problems. It's full of something known as Silymarin, which has been the focus of said research, being found to be an effective therapeutic treatment for nonalcoholic fatty liver disease . It's also commonly promoted as a treatment for everything from jaundice, hepatitis, cirrhosis, and many other conditions .
Dosage here is difficult to really put your finger on, as if the extract is pure enough (50% or above) then you can get away with just 50mg of the stuff, whereas less pure extracts would require anything from 250 to 750mg to be effective .
Beyond this, there's still Bupleurum Extract ,Wild Yam Root ,Lycium (Goji Berry) ,Dandelion Root ,Oregon Grape Root, Ginkgo Biloba, Reishi Mushroom, Schisandra, Chinese Salvia, Dandelion Leaf, Gynostemma, Barberry, Tribulus, Watercress, Grape Seed, Ginger Root, Cardamom, Turmeric Root, and Maitake Mushroom. As you can see, there's simply not enough room so let's move swiftly on
Well that's crystal star liver renew. It's quite a common sight in natural supplements unfortunately, so we're not so surprised to see it here. The public discourse surrounding such supplements has skewed public opinion to be distrustful of most natural supplements. It's understandable when you're looking for something to help ease some pain, and you're met with overly large ingredient lists that are made in such a way to cause as much confusion as possible, whilst simultaneously wrapping their products in as many buzz words as possible.
Luckily there are genuinely positive supplements out there that can not only help with your problems, but are honest in how they go about it. Take Leber Cure for example, it's a genuinely genius formula that gather all of the best herbal, therapeutic medications for liver health and combines them to offer a convenient, one stop solution to your issues. Now it's understandable you'd be cautious, which is why we urge you to check it out for yourself. There's no subterfuge to be found, just clear, concise communication about what their product is, as well as how and why it will help you develop a more healthy liver.
Ofcourse everyone makes such claims, but that's what we're here for. If Liver Renew instead chose to simply offer it's better ingredients at a reasonable dosage, and dropped the baggage of endless filler, it'd be something we'd gladly recommend. As it stands however, we simply can't do that because even though we can infer a few ingredients are likely properly dosed, we can not guarantee it.
1 - https://pubmed.ncbi.nlm.nih.gov/31804025/
2 - https://pubmed.ncbi.nlm.nih.gov/34591699/
3 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348909/
4 - https://pubmed.ncbi.nlm.nih.gov/23195590/
5 - https://www.ncbi.nlm.nih.gov/books/NBK541075/
6 - https://www.nccih.nih.gov/health/milk-thistle
7 - https://www.ncbi.nlm.nih.gov/books/NBK548817/