Best Probiotic Supplements 2022

What are the best probiotic supplements, and should you take them?

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What Do We Look For In The Best Probiotic Supplements?

Probiotics comprise live bacteria and yeasts that are considered beneficial to human health. It is thought that probiotics are beneficial to our gastrointestinal tracts and may also boost the immune system as well as potentially reducing the risk of upper respiratory tract infections. While probiotics are found naturally in certain foods (such as fermented yogurts, sauerkraut, and kimchi), a wide range of probiotic supplements are available on the market that purports to promote a range of health benefits. In this article, we’ll investigate the best probiotic ingredients and some of the best regarded probiotic supplements available today.

We rate the best probiotics based on: 

bacteria quality, immune support, digestive health, value, USP and customer satisfaction


Yourbiology +
- BestProbiotic Overall 

Biotics 8
- Best Probiotic For Men

Nuzena - Best Value Probiotic

Mary Ruth's
- Best Probiotic For Children

Common Ingredients In Quality Probiotics

While probiotic supplements often contain a blend of popular and essential probiotic strains, here are some of the most common ingredients you’ll find on a label.


Among the most common probiotic found in foods, lactobacilli are diverse and can help treat a range of ailments, including diarrhea, vaginal infections, and eczema. Often used as a starter culture in food production, lactobacilli are often found in wine, beer, cheese, fermented yogurt, kefir, and other fermented foods. 


Normally found within the intestines and stomach, bifidobacteria is a group of probiotics that help the body digest food and combat harmful bacteria. Although found within the body, bifidobacteria can be consumed safely through yogurt (with added cultures), cured meats, buttermilk, and fermented foods. It is thought that the bacterium can help treat irritable bowel syndrome (IBS), constipation, lung infections, and ulcerative colitis.

Saccharomyces boulardii

A common yeast, Saccharomyces Boulardii is a strain of saccharomyces cerevisiae that is usually used to help treat certain types of diarrhea, including rotaviral diarrhea in children, diarrhea caused by rotavirus, and travelers’ diarrhea.

Now that we’ve covered three of the most common probiotic ingredients, let’s look at some of the best probiotic supplements available in 2022.

Best Probiotics FAQ

What are the best probiotic supplements?

Should I Take A Probiotic After Anti Biotics?

The general consensus of the medical community is yes. Anti biotics kill a lot of your healthy bacteria and taking a probiotic following a course will help restore that quickly and effectively returning your microbiome to a healthy state.

Do Probiotics Work?

Ultimately this depends what you mean by work, will they improve digestive health and offer immune support. Yes. The science is definitely in on that one. However, with regards to certain other claims, results are still inconclusive, several probiotic supplements make some wild claims around weight loss, stress relief and we've even seen some claiming to be nootropics, there are better dedicated supplements for that. 

Are Probitics Safe?

In 99% of cases yes, probiotics are safe.  In many cases you can also take them if you are on antibiotics and they may actually prevent some stomach issues, although there is still some ongoing debate as to timings and whether or not they should be taken at all. The general consensus is moving towards taking them being recommended [1]

 However, some cancer patients and people recieving intense treatments can have adverse reactions, so in these cases it is best to check with a doctor. 

YourBiology Gut+ - Best Probiotic Overall

A probiotic supplement heralded by many as the best probiotic on the market, ​YourBiology is designed by an experienced team of scientists and includes a range of crucial probiotic ingredients, including Lactobacillus Acidophilus, Bifidobacterium Lactis, Lactobacillus Paracasei, and Fructooligosaccharide.

Packed with friendly probiotic strains the supplement is said to enhance skin health, strengthen immunity, improve digestion, increase energy, and reduce stress. What’s more, ​YourBiology claims the formula provides an increased survival rate of 250 times compared to the competition.

This benefit is noteworthy, as rival brands can only claim that “most” probiotics will reach the gut. In contrast, this unique formula contains only high-quality strains of bacteria to deliver superior results. With fewer bacteria being killed and digested in the gut, ​YourBiology probiotics are widely regarded as the market's most influential and best probiotic supplement.

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Probiology Ingredients 

LA-14 has multiple studies showing that it plays a role in improving immune performance. [2] It also as you'd expect improves digestion. 

BL-04 is another immuno boosting probiotic, shown to be effective in double blind placebo controlled trials [3] it's another great ingredient that we like to see here. Bifidobacterium lactis, is a great choice and well backed. 

LP-115 is interesting, in a lot of cases a large portion of this bacteria stuggles to make it to the digestive tract whereas probiology plus took extra effort to include extra to make sure the right amount makes it through to be effective. Shown to be particularly effective at treating bowel issues, and boosting immune response. [4] 

LPC-37 has huge implications beyond simply helping improve digestion, it's been shown to improve physiological markers of stress and anxiety in healthy adults in double blind trials. [5] Whilst this is still not fully understood the science looks interesting, and as a minimum it will improve gut health.

How Long Does Yourbiology Take To Work

While ​YourBiology's probiotic claims that the probiotics will start working straight away, the brand has outlined a useful timetable to highlight the supplements' effects over a few months.

Two weeks of regular intake: Good digestion, less bloating, better moods, and clearer skin should be noticeable

One month of regular intake: Less brain fog, improved metabolism, regular bathroom breaks, and better immune health

Two months of regular intake: Excelled health improvement and fewer ailments and health issues

Three months of regular intake: Robust digestion, fresher and lighter outlooks, and massively improved skin health

What Do Customers Say?

Customer reviews are very positive, often citing the supplements’ ability to provide noticeable results in as little as two weeks. Moreover, those who have tried multiple brands often report that ​YourBiology is their favored supplement.

Best Way To Use Yourbiology

As directed by YourBiology, the supplements are best taken as capsules every morning with a glass of water.  It is recommended to take the dosage over a few months to enjoy the full benefits of the supplements. It’s worth noting that ​YourBiology does not offer a monthly subscription model, unlike some supplement companies.

Criteria Rating
Bacteria quality 9/10
Immune support 10/10
Digestive health 10/10
Customer satisfaction 10/10
Value 9/10
Recommended 9/10
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