Published November 30th 2023
Fact Checked by Dr Mark Watson
You really don’t get a lot for what you pay for in Osteovantiv. We’ve got magnesium, Iso Alpha Acids and some standardized cartilage. The later is a fancy name for Type II collagen, found in pretty much every $20 joint supplement, along with ingredients that are going to do more good for joint pain too. Magnesium is pretty low tier in terms of vitamins an minerals that are important for joint health, and there’s a good 5 or 6 that would do more, and are more common deficiencies. Which leads us to the question are the Iso Alpha Acids going to be enough to justify Osteovantiv costing $70 a bottle. Well no, not even close. There are a good dozen far more well backed natural ingredients than the extract from hops. And that’s not to say that there’s no potential for it to help at all. Just that it’s only really been proven in animal studies, and only one study has been done in humans, with double the dosage.
Whereas the likes of curcumin (the extract from turmeric), capsaicin, omega 3, glucosamine, resveratrol, bromelain and about a dozen other ingredients all have human studies to back their use. True a lot of cheaper supplements have these ingredients at ineffective doseages, but there are options at the $60 price point that do in fact contain these ingredients in their correct dosing.
As a result, there’s no way we can recommend Osteovantiv. Compared to something like FlexAgainwhich doses 11 ingredients all more well studied and shown to be more effective than the ones in Osteovantiv at a lower price, and with a money back guarantee there really isn’t a contest.
In short, we don’t recommend Osteovantiv.
Surprisingly the reviews are quite good, but it does seem
like Osteovantiv have refunded quite a few of the people who previously left negative
reviews and updated them, which does of course improve the overall 4* rating.
That said, most of the other reviews are still in fact positive, with a lot of people saying it has in fact helped with joint pain.
All in all we do have to say that there does seem to be evidence that the customer base does like Osteovantiv at least.
When it comes to the negative reviews of Osteovantiv most people just say that quite simply it isn’t worth the price.
Magnesium 37.5mg – This is only 9% of your RDI, meaning that
it’s not going to do a whole lot to improve joint health, unless your mildly deficient.
And it’s magnesium oxide meaning it’s the cheapest and least bioavailable form
of magnesium possible. So, even though we said it’s 9% of your RDI, it’s more
like half that. If you consider that you can get a decent magnesium supplement
for $10 that will actually make a difference you’re better off doing just that rather
than getting it from Osteovantiv.
Now as to whether magnesium belongs in here at all, it is true that a deficiency in magnesium can cause joint pain,  but, it’s not going to do much unless you are. And considering vitamin D deficiency can cause the same,  and most studies suggest that more than 50% of American’s over 50 are deficient, the amount you need would actually fit in this capsules, which one would’ve made more sense.
Standardized Cartilage 20mg – As we said this is a fancy word for type II collagen, there are a reasonable amount of studies on it’s effectiveness for joint pain.  And ultimately the results have to date been relatively inconclusive with as many studies suggesting it does nothing as those that have found some use. There’s reasonable anecdotal evidence as a lot of people swear by it, but as we said, this is available in a lot of cheaper supplements. This could be the ingredient doing the heavy lifting in Osteovantiv.
Iso-Alpha Acids 300mg – This is Osteovantiv’s selling point, and unfortunately it’s not a great one. The hops extract is an interesting choice, and in a better supplement would’ve probably been an interesting extra element to include. There are some studies on it’s effectiveness for reducing inflammation and joint pain, but most of the studies are in animals or test tubes meaning that we don’t actually know if it has any real life implications or if this is even within the effective dosage range for humans.
There has been ONE human trial on hops containing a standardized amount of this extract, but it used 2 grams at a 30% standardization, this means that the dose was double what we have in Osteovantiv. . And whilst the trial in question was small, only 57 people including the placebo group, self reported pain levels were lower in those that took the extract. So, it’s not that there’s no evidence at all here. But, one study isn’t really great backing considering the ingredients we mentioned in the intro have far more.
All in all Osteovantiv is not terrible, but it is very
overpriced. It’s also incredibly unproven, it relies heavily on two ingredients,
one of which has very mixed studies and the other only has one human trial that
used double the dose in Osteovantiv.
Meaning that it’s anybody’s guess if it’s going to work. Which could be fine for a $20 supplement, as we could simply say give it a go and see.
But, at their $70-100 price point depending on where you buy, it doesn’t hold up. Not when that’s the same price point as the best options on the market. Which contain a lot more proven ingredients, and offer money back guarantees.
Ultimately, we recommend you either try out a simple hops pill for half the price, or if you want a comprehensive joint supplement then we recommend trying FlexAgain, who we’ve rated the number 1 joint supplement on the market for the last 2 years.
1 - https://pubmed.ncbi.nlm.nih.gov/34023805/
2 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413222/
3 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620403/
4 - https://austinpublishinggroup.com/nutrition-metabolism/fulltext/ajnm-v9-id1124.pdf