We really liked the idea of Bio X4, a weight loss aid that targets both the probiotic supplement side of things and includes ingredients that help manage appetite and cravings. It's just a shame that they completely missed the mark on the appetite suppression and craving control blend. And we do mean completely. They decided in their infinite wisdom to use the two worst ingredients in modern weight loss supplements for these aspects and as you'd expect this is going to be reflected in our Bio X4 review.
Green tea extract is something we're barely OK with in a weight loss supplement, it doesn't come close to functioning as well as glucomannan for hunger management, doesn't really provide any thermogenic benefit and is an all around low tier option. As for the craving control blend, the less said about it the better, the only ingredient in said blend, Caralluma Fimbriata, has been shown to have no impact in humans (there were previously some successful studies in animals, which is clearly how this ingredient made it into Bio X4). There is an option that does actually work, 5HTP, previously only available from clinicians, it's now available over the counter and has been proven to be effective in both trials and understood well enough that it's effects can been seen via brain scan when people were shown to have less interest in high calorie foods after taking the supplement.
If the question is does bio x4 work? The answer is yes, but negligibly and you'd be far better off with a focused weight loss aid like hourglass fit (which contains both glucomannan and 5htp) and a probiotic supplement.
Bio X4 claims that it will improve gut health, manage cravings, aid weight management and boost metabolism. The first claim we have no issues, it will improve gut health. Everything else is where the pseudoscience comes in. There is some evidence to suggest that a healthier gut will help with cravings. However, most of this is correlation data, and you also have to change your dietary habits which in and of itself will help cravings drop over time.
Most of the studies show that there isn't really much evidence to support the efficacy against a placebo.As for weight management, they rely heavily on the green tea extract, which whilst it is in a lot of good fat burners, it's usually the last ingredient thrown in to bulk out the mix as it's benefits are negligible compared to others.As for boosting metabolism, there isn't any real evidence to suggest that a probiotic supplement can do this.
Want to find the best fat burner for you? Not sure if Bio X4 is what you're looking for, then check out our list of the best on the market in 2022.Best Fat Burners
Customers Bio x4 reviews were a mixed bag, and we can't say we're surprised, if customers were just using it as a general probiotic for gut health, then it would probably be "ok" although even then there's far better alternatives, but the fact that it promises weight loss as so many probiotic supplements seem to be recently there are a lot of negative reviews. The reality is that more reviews than not said that Bio X4 did not help them lose weight. Although most did also say it helped with digestive issues.After we filtered out fake reviews the average seemed to be around 3*, which is actuually a little better than what you'd probably expect from something that only does half of what it promised.
We answer some of the most commonly asked questions about Bio X4.
No, at least not in the way it claims, if the question however was is bio x4 a scam? We'd also say no. It does sort of work, just barely.
The ingredients breakdown for Bio X4 is going to be relatively short, we've got a few bacteria and some ineffective weight loss supplements.
We've got the full named versions of the following enzymes:
Amylase which breaks down sugars.
Lipase a digestive enzyme which targets fat.
Bromelain is an enzyme which breaks down protein.
This is all fine in a probiotic, nothing to see here.
Then we have the green tea extract for weight management. This really is only negligably effective. Then we have Caralluma Fimbriata to which one study of 60 people backed it's use  every other study however has found this not to be the case, which is why it doesn't make it into any other weight loss aid.
Next up is the Lactobacillus blend, this is actually fine, most people aren't short of these bacteria included in bio x4 supplements. But at the same time there's nothing wrong with it being here. It just isn't going to do anything to help you lose weight.
The last part of nucific's bio x4 supplement is it's bifidobacterium, these are the bacteria that live in and around the intestines.
They help combat diarrhea and help maintain a healthy intestinal tract, but again nothing to do with weight loss.
In short Bio X4 is part of a growing trend of just slapping weight loss on the side of a health product and telling the marketing team to "go get em" not actually a weight loss product. This is really common with probiotics right now because a couple of sketchy studies showed some correlation with gut health and weight loss, but most didn't account for healthy eating itself improving gut health.
Which is a shame, because to be quite honest they've come closer to making something that actually does this job properly when they started to include ingredients that you'd actually see in a dedicated appetite suppressant or fat burner, which does actually make them a little bit better than their closest competitor biofit who didn't even bother to do that.The idea is good, the execution is terrible.
We can only assume that Bio X4 chose green tea extract to save money. In short, Bio X4 is not a good supplement for anybody, never mind anybody trying to lose weight. The digestive enzymes are fine, but you could get a better blend of healthy bacteria from other cheaper competitors and your weight loss efforts would be far better supported by a proper weight loss supplement like hourglass fit. We'd recommend you pass on Bio x4 and get a cheap probiotic along with one of the best fat burners.
Want something better than Bio X4? Check out our best fat burners for men list.Best Fat Burners
1 - https://pubmed.ncbi.nlm.nih.gov/26093535