Primal Flex is, in a nutshell, an 'ok' joint health supplement. It's not a great one, but it's not the worst either. There are superior joint health supplements on the market, and while Primal Flex isn't the most expensive option, it's not cheap either.
There’s a few issues with the dosages in Primal Flex ingredients, for example, turmeric needs to be dosed with at least 500mg of curcumin to be effective  of which Primal Flex only contains 100mg of turmeric, which equates to about 20mg of curcumin, which simply isn’t going to be effective at producing it’s anti inflammatory qualities. Or perhaps even more laughably the 2mg of Ashwagandha, this needs to be in the 600mg range to do anything at all, and isn’t even particularly well backed as a joint supplement.
On the positive side, Primal Flex does dose some of its herbal extracts such as Boswellia and type ii collagen correctly, but considering you can get all of these in $19/month joint supplements that does have us wondering what the point of Primal Flex actually is. Ultimately everything else beyond what you’d expect to pay half the price for is dosed so low that it won’t work, meaning that we don’t recommend Primal Flex.
Especially considering the fact that their price point has them come up against the likes of FlexAgain, which contains all the same effective ingredients and more for $5 a month more it really isn’t a contest.
In terms of
customer reviews, Primal Flex has received mixed feedback. Some users report
significant improvements in joint pain and mobility, while others have noticed
little to no effect. This isn’t really surprising seeing as Primal Flex is relying
on Boswellia and Type ii collagen to do it’s heavy lifting and these are well
known to have very mixed success rates.
Primal Flex's Amazon reviews clearly contain a few poorly written fakes, although some of the positive ones do seem to be completely legitimate.
On the positive side there were very few complaints of Primal Flex side effects although there were some people who complained of severe gastric distress.
This variability in user experiences further highlights the fact that joint health supplements, like all health supplements, do not work the same way for everyone.
Vitamin C 200mg
– This is 222% of your daily dose and a deficiency can lead to joint issues, so
it’s not a terrible inclusion on the face of things. The problem is that Primal
Harvest is looking at vitamin c from an injectable standpoint. Vitamin C
injections have been shown to improve osteoarthritis symptoms  at this dose,
but unfortunately the efficacy doesn’t apply to oral consumption. So enough to
make sure you hit your RDI would be good, but taking up this much capsule space
is largely a waste.
Magnesium 97mg – As magnesium oxide isn’t the most bioavailable form, coming in at only 22% of the RDI it’s not the best inclusion. Again it can have some benefit for joint health and low magnesium has been connected to OA progression . So, it’s not a bad inclusion, but the reason combined supplements don’t often contain magnesium is that the versions your body can actually absorb are very large and usually only contain 15% magnesium. As such you normally need a full capsule just for the magnesium to be in an affective dose.
Biocell collagen 500mg – This is made up of type ii collagen, chondroitin and hyaluronic acid, and whilst type ii collagen has been shown to be effective , hyaluronic acid only works via injection  as the stomach breaks it down and chondroitin is simply a supporting ingredient which increases the effectiveness of glucosamine, which isn’t actually present in Primal Flex.
Turmeric 100mg – Turmeric is actually a good ingredient for a joint supplement, the problem as we mentioned in the intro is quite simply that there is nowhere near enough of the active ingredient curcumin to be effective here. 
Eggshell membrane 100mg – Eggshell isn’t the worst ingredient, and recent meta analysis has shown that it has resulted in statistically significant increases to mobility for joints vs placebo’s  however, once again with Primal Flex we have an issue of dosage as this is about 10x lower than what is recommended.
Boswellia 100mg – Boswellia is a pretty common inclusion in joint supplements, and it’s been shown to be effective at 100mg as an anti inflammatory and for joint pain relief, so no issues with this one. 
Black Pepper 10mg – Black pepper or bioperine has been shown to improve the absorption rate of nutrients so it’s generally an ok ingredient for most supplements.
Ashwagandha 2mg – Ashwagandha does have some anti inflammatory properties, but the smallest amount that has ever shown results in a clinical trial is 250mg . As such it’s not going to do anything in a 2mg dose.
Astaxanthin 2mg – And once again we have another ingredient that could work for osteoarthritis progression specifically if it was correctly dosed (at 10mg/lb of body weight) and it is nowhere near that.  Even with that in mind the research is relatively new and there hasn’t been much evidence since a study conducted in 2019, so again a good idea, but poor execution from Primal Flex.
In conclusion, Primal Flex is a sub par option if you're looking for a joint health supplement. It contains several key ingredients known to support joint health but falls short in terms of dosage meaning that ultimately it will be no more effective than other cheaper joint supplements and is nowhere near as potent as the competitors in it’s price bracket. And seeing as there are other products on the market that offer far better value for money and more comprehensive joint health support we don’t recommend Primal Flex. It’s not that it won’t do anything for you. But, it’s not great either.Best Joint Supplements
1 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812094/
2 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543556/
3 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444049/
4 – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222752/
5 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135165/
6 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7989856/
7 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368679/